Spirit
Mind
noun
Your spirit spirit is… your spirit. This word is for the human mind and can refer to your mental state, thinking, attitude, mindset, or even willpower.
Depending on the context, 精神 can also mean "spirit" as in the essence or core principle of something, like 独立の精神 (the spirit of independence).
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.
私の父は、精神を病んで精神病院に通っています。
My father is mentally ill and goes to a mental hospital.
精神を集中して勉強すれば、一ヶ月で日本語がペラペラになるよ。
If you focus your mind and study hard, you'll be fluent in Japanese in a month.
うちの学校は自由と独立の精神の重んじているので、校則がありません。
Our school values the spirit of freedom and independence, so there are no school rules.