To Be Used Up
To Be Exhausted, To Run Out
intransitive verb, ichidan verb
Because the hiragana ends with an う sound, you know this word is a verb. The kanji itself means use up or exhaust, and this verb is to be used up, to be exhausted, or to run out.
If something is exhausted it's because you used up too (つ) much of it, and now it's all gone.
ついに食料の備蓄が尽きた。
Our food stockpile ran out in the end.
人は、命が尽きる瞬間が一番輝いていると思わない？
Don't you think people shine brightest at the end of their lives?
長い髪を手櫛で梳かしながら、彼女は僕に、あんたにはもう愛想が尽きたわと言った。
While combing her fingers through her hair she told me that she had already fallen out of love with me.