Hardship
Difficulty, Hard, Difficult
noun, な adjective
You're distressed and it's difficult. This is quite the hardship and difficulty you're feeling.
This is a jukugo word that uses the on'yomi readings of the kanji. You should be able to read this on your own.
私、仕事で困難に直面すると、ワクワクするんです。
I get excited when I face difficulties in my work.
このレストランはとても人気で、予約が困難なことで有名です。
This restaurant is very popular and is known for its difficulty in making reservations.
私はそれが原因で、歩行困難になってしまいました。
It caused me to have difficulty walking.