Problem
Question
noun
The problem topic is the problem or question you have to answer. If you think about it, topics as problems tends to be a school-related thing. So, when you have to answer a problem in school, that's 問題.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.
ワニカニの売り上げが落ちるのはトーフグにとって大きな問題です。
It would be a big problem for Tofugu if WaniKani's revenue were to drop.
この数学の問題、全然分からないんだけど。
I don't understand this math problem at all.
「週末、私の犬の世話をしてもらえないかな?」「問題ないよ。任せといて。」
"Can you look after my dog for the weekend?" "No problem. You can count on me."