Unpleasant
Uncomfortable
noun, な adjective
Things that are not pleasant are unpleasant or uncomfortable.
This is a jukugo word, which usually means on'yomi readings from the kanji. If you know the readings of your kanji you'll know how to read this as well.
この服は生地がザラザラしていて不快に感じます。
The fabric of this clothing feels rough, and I find it uncomfortable.
あなたに触られるととっても不快なんです。
It feels really unpleasant when you touch me.
そういうコメントが他人を不快にさせる可能性があるってこと、なんで分からないの？
How can you not realize that comments like that might make others uncomfortable?
上司の不快なジョークに笑いたくもないのに笑っている自分が嫌いです。
I don't want to laugh at my boss's unpleasant jokes and I hate myself when I do.