Sake
Alcohol
noun
This is just the noun version of the kanji 酒 - it has an お there to be nice. This word can mean both alcohol (like the parent kanji) or sake (the main kind of Japanese alcohol, at least back in the kanji days).
The reading is kun'yomi, which isn't what you learned with the kanji. But, it should be pretty easy. You know what Japanese alcohol is called already, right? It's さけ, simple as that. So long as you've heard of sake you should be A-Okay with this reading.
お酒をたしなむ
to like to drink alcohol every now and then, to drink just to be sociable
お酒を買う
to buy alcohol
お酒を飲む
to drink alcohol
このドリンクはお酒が入ってますか？
Does this drink contain alcohol?
日本で、お酒を飲めるのは二十才以上の大人だけです。
In Japan, only adults over twenty years old can drink.
お酒に弱いので、お茶をいただきます。
I don't have much alcohol tolerance, so I will have tea.